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Does timolol work at night? It has been shown that beta-blockers do not lower IOP at night and that systemic absorption may decrease BP to the point that it impairs ON perfusion. Acetazolamide but not timolol lowers aqueous humor flow in sleeping humans.
What size bottle does combigan come in? the 10mL bottle size of brimonidine/ timolol (Combigan) is equivalent in drug composition to the existing 5mL format and should be cost-neutral to the program.
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