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Can metformin cause liver or kidney damage? CONCLUSION: Metformin does not appear to cause or exacerbate liver injury and, indeed, is often beneficial in patients with nonalcoholic fatty liver disease. Literature evidence of liver disease being associated with metformin -associated metabolic acidosis is largely represented by case reports.
What are the first signs of diabetic neuropathy? Signs and symptoms of peripheral neuropathy are often worse at night, and may include: Numbness or reduced ability to feel pain or temperature changes. Tingling or burning sensation. Sharp pains or cramps. Increased sensitivity to touch — for some people, even the weight of a bedsheet can be painful. Muscle weakness.
Can metformin make diabetes worse? Could Metformin Actually Make Insulin Resistance Worse ? Polycystic Ovarian Syndrome, or PCOS, and Insulin Resistance (IR) often occur simultaneously. While the connection between these two conditions is, as of yet, not entirely clear, researchers have determined that IR can lead to PCOS and diabetes.
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