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What is the difference between venlafaxine and DULoxetine? Cymbalta (duloxetine) and Effexor XR (venlafaxine) are selective serotonin and norepinephrine reuptake inhibitor (SNRI) antidepressants used for treating depression and anxiety disorders. Cymbalta also is used for the treatment of diabetic peripheral neuropathic pain, fibromyalgia, and chronic musculoskeletal pain.
Is it better to take Cymbalta in the morning or at night? It is best to take duloxetine at the same time each day. Most people take it in the morning. If you find that you feel drowsy after taking it in the morning, try taking it in the evening. The capsules should be swallowed whole, with a glass of water.
Does Cymbalta make you sleepy or awake? Cymbalta may make you feel drowsy and may affect your judgment. Until you know how Cymbalta will affect you, you should not drive or operate machinery. Drinking alcohol may increase some serious side effects of Cymbalta. Cymbalta may cause high blood pressure.
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