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Is PBC reversible? The cause of fatigue in PBC is unknown and can be very debilitating. As mentioned above, jaundice occurs when PBC is very severe. Sometimes, it can be reversed with treatment of the PBC, but sometimes, patients who have jaundice will require a liver transplant.
Can you die suddenly from liver failure? Acute liver failure can develop suddenly in an otherwise healthy person and requires immediate medical attention. Acute liver failure is a medical emergency that can cause complications including excessive bleeding, pressure in the brain (cerebral edema), kidney failure, infection, and death.
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